Free Printable WorksheetScienceGrade 10Science CurriculumBIO.10.106

10.106 Endocrine Feedback and Hormonal Regulation Worksheet

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Worksheet Overview & Skills Covered

Core academic competencies and curriculum alignment

This Biology Science worksheet provides structured practice on 10.106 Endocrine Feedback and Hormonal Regulation. Students are guided through targeted exercises that build foundational understanding, computational accuracy, and critical thinking skills.

Endocrine Feedback and Hormonal Regulation: Students analyze how hormones, receptors, glands, target cells, and negative feedback regulate processes such as glucose balance, growth, reproduction, and stress responses. Rigor range: standard concept checks through honors/Pre-AP/AP-ready integrated physiology, plant systems, health data, and applied decision-making.. Aligned to FreeK12Practice High School Biology Curriculum Crosswalk (NGSS/NRC Framework; CCSS Literacy and Mathematics; AP Biology enrichment; Texas TEKS Biology; Florida NGSSS/CPALMS Biology; Virginia SOL Biology; California NGSS and New York State Science Learning Standards) BIO.10.106 - Endocrine Feedback and Hormonal Regulation: Corresponding standards copied from the curriculum for skill 10.106: National: NGSS HS-LS1-2; HS-LS1-3; DCI LS1.A; CCC Cause and Effect; CCSS RST.9-10.7; RST.11-12.7; HSS.ID.C.7; AP Biology SYI-3, IST-3, SP4, SP5. State frameworks: TX TEKS BIO.12A, BIO.12C; FL NGSSS SC.912.L.14.52; VA SOL BIO.3b, BIO.3d; CA NGSS/NYSSLS HS-LS1-2, HS-LS1-3.

Whether you are an educator preparing classroom handouts, a tutor reinforcing weekly topics, or a parent supporting homeschool learning, this printable resource gives students the deliberate practice required to achieve subject fluency and master state standards.

Grade

Biology

Subject

Science

Domain

Science Curriculum

Formats

PDF & DOCX

Sample Practice Problems

Preview the types of problems and questions covered in this worksheet

Below are sample questions representative of the exercises included on this worksheet and related 10.106 Endocrine Feedback and Hormonal Regulation skill assessments:

Problem 1Difficulty: Mastery

In the reproductive endocrine axis, the gonads are removed in an experimental model while the hypothalamus and pituitary remain functional. Which pattern is most likely after feedback stabilizes?

ASex steroid levels are high, while GnRH, LH, and FSH all fall to zero

BThe pituitary releases insulin instead of LH and FSH

CThe hypothalamus stops releasing hormones because gonads make GnRH

DSex steroid levels are low, while GnRH, LH, and FSH tend to rise

Solution & Explanation:Removing the gonads lowers sex steroid output. Reduced negative feedback allows hypothalamic and pituitary signals such as GnRH, LH, and FSH to increase.

Problem 2Difficulty: Mastery

Use the fasting graph. As blood glucose decreases over 12 hours, glucagon increases. Which statement best describes the relationship shown?

ABlood glucose and glucagon rise together at the same rate

BGlucagon remains zero whenever glucose changes

CBlood glucose and glucagon show an inverse relationship during the fasting period

DThe graph proves that insulin is released by alpha cells

Solution & Explanation:The graph shows glucagon increasing as glucose decreases, which is an inverse relationship consistent with glucose feedback.

Problem 3Difficulty: Mastery

Use the hormone-treatment data. Cells with Receptor S show enzyme activity of 20 units without hormone and 78 units with Hormone S. Cells without Receptor S stay near 20 units with or without hormone. Which claim is best supported?

AHormone S changes enzyme activity equally in all cell types

BHormone S changes enzyme activity only when Receptor S is present

CReceptor S prevents cells from responding to Hormone S

DThe data prove Hormone S is a steroid hormone

Solution & Explanation:Only receptor-positive cells show a large change after hormone treatment, supporting receptor-dependent response.

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QWhat grade level and standards does this worksheet align with?

This worksheet is designed specifically for Biology Science students. It aligns with educational standard BIO.10.106 (Corresponding standards copied from the curriculum for skill 10.106: National: NGSS HS-LS1-2; HS-LS1-3; DCI LS1.A; CCC Cause and Effect; CCSS RST.9-10.7; RST.11-12.7; HSS.ID.C.7; AP Biology SYI-3, IST-3, SP4, SP5. State frameworks: TX TEKS BIO.12A, BIO.12C; FL NGSSS SC.912.L.14.52; VA SOL BIO.3b, BIO.3d; CA NGSS/NYSSLS HS-LS1-2, HS-LS1-3.).