Free Printable WorksheetScienceGrade 10Science CurriculumBIO.10.18

10.18 Nucleic Acids and ATP Worksheet

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Worksheet Overview & Skills Covered

Core academic competencies and curriculum alignment

This Biology Science worksheet provides structured practice on 10.18 Nucleic Acids and ATP. Students are guided through targeted exercises that build foundational understanding, computational accuracy, and critical thinking skills.

Nucleic Acids and ATP: Students connect nucleotides to DNA, RNA, and ATP, explaining how nucleic acids store information and ATP transfers usable cellular energy. Rigor range: standard concept checks through honors/Pre-AP/AP-ready structure-function and biochemical data interpretation. Aligned to FreeK12Practice High School Biology Curriculum Crosswalk (NGSS/NRC Framework; CCSS Literacy and Mathematics; AP Biology enrichment; Texas TEKS Biology; Florida NGSSS/CPALMS Biology; Virginia SOL Biology; California NGSS and New York State Science Learning Standards) BIO.10.18 - Nucleic Acids and ATP: National: NGSS HS-LS1-1; HS-LS1-6; DCI LS1.A, LS1.C; CCSS RST.9-10.2; RST.9-10.7; AP Biology IST-1, ENE-1. State frameworks: TX TEKS BIO.5A, BIO.7A, BIO.11A; FL NGSSS SC.912.L.16.3, SC.912.L.18.1, SC.912.L.18.10; VA SOL BIO.2b, BIO.5a; CA NGSS/NYSSLS HS-LS1-1, HS-LS1-6.

Whether you are an educator preparing classroom handouts, a tutor reinforcing weekly topics, or a parent supporting homeschool learning, this printable resource gives students the deliberate practice required to achieve subject fluency and master state standards.

Grade

Biology

Subject

Science

Domain

Science Curriculum

Formats

PDF & DOCX

Sample Practice Problems

Preview the types of problems and questions covered in this worksheet

Below are sample questions representative of the exercises included on this worksheet and related 10.18 Nucleic Acids and ATP skill assessments:

Problem 1Difficulty: Mastery

Which claim best integrates nucleotide structure with both genetic information and cell energy?

AAll nucleotides have identical roles, so ATP, DNA, and RNA are interchangeable in cells.

BOnly proteins contain nucleotides, so DNA and ATP are protein polymers.

CNucleotides store information only when they have no sugars or phosphates.

DDNA and RNA use nucleotide sequences for information, while ATP uses nucleotide-related phosphate transfer for energy coupling.

Solution & Explanation:DNA, RNA, and ATP all connect to nucleotide chemistry, but structure determines function. DNA and RNA depend on sequences; ATP depends on phosphate transfer.

Problem 2Difficulty: Mastery

A DNA diagram marks one strand 5'-A C G T-3'. Which paired strand direction and bases are correct?

A5'-T G C A-3'

B3'-U G C A-5'

C3'-T G C A-5'

D5'-A C G T-3'

Solution & Explanation:DNA strands are antiparallel and complementary. Across from 5'-A C G T-3' is 3'-T G C A-5'.

Problem 3Difficulty: Mastery

Two DNA sequences differ at one position: Sequence 1 is ACGTAC and Sequence 2 is ACGGAC. What type of nucleotide-level change is shown?

AA change in the sugar-phosphate backbone only

BA base substitution

CATP hydrolysis of the entire sequence

DA conversion of DNA into a triglyceride

Solution & Explanation:The sequences are the same length and differ at one base position, where T has been replaced by G. That is a substitution.

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Frequently Asked Questions

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QWhat grade level and standards does this worksheet align with?

This worksheet is designed specifically for Biology Science students. It aligns with educational standard BIO.10.18 (National: NGSS HS-LS1-1; HS-LS1-6; DCI LS1.A, LS1.C; CCSS RST.9-10.2; RST.9-10.7; AP Biology IST-1, ENE-1. State frameworks: TX TEKS BIO.5A, BIO.7A, BIO.11A; FL NGSSS SC.912.L.16.3, SC.912.L.18.1, SC.912.L.18.10; VA SOL BIO.2b, BIO.5a; CA NGSS/NYSSLS HS-LS1-1, HS-LS1-6.).