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10.62 Meiosis I and Meiosis II Worksheet

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Worksheet Overview & Skills Covered

Core academic competencies and curriculum alignment

This Biology Science worksheet provides structured practice on 10.62 Meiosis I and Meiosis II. Students are guided through targeted exercises that build foundational understanding, computational accuracy, and critical thinking skills.

Meiosis I and Meiosis II: Students sequence meiosis, identify homologous chromosomes and sister chromatids, and explain how chromosome number is reduced to form gametes. Rigor range: standard concept checks through honors/Pre-AP/AP-ready sequence, probability, pedigree, population, and bioethics analysis. Aligned to FreeK12Practice High School Biology Curriculum Crosswalk (NGSS/NRC Framework; CCSS Literacy and Mathematics; AP Biology enrichment; Texas TEKS Biology; Florida NGSSS/CPALMS Biology; Virginia SOL Biology; California NGSS and New York State Science Learning Standards) BIO.10.62 - Meiosis I and Meiosis II: National: NGSS HS-LS3-1; HS-LS3-2; DCI LS3.A, LS3.B; CCSS RST.9-10.3; RST.9-10.7; AP Biology IST-3. State frameworks: TX TEKS BIO.8A; FL NGSSS SC.912.L.16.16, SC.912.L.16.17; VA SOL BIO.5d; CA NGSS/NYSSLS HS-LS3-1, HS-LS3-2.

Whether you are an educator preparing classroom handouts, a tutor reinforcing weekly topics, or a parent supporting homeschool learning, this printable resource gives students the deliberate practice required to achieve subject fluency and master state standards.

Grade

Biology

Subject

Science

Domain

Science Curriculum

Formats

PDF & DOCX

Sample Practice Problems

Preview the types of problems and questions covered in this worksheet

Below are sample questions representative of the exercises included on this worksheet and related 10.62 Meiosis I and Meiosis II skill assessments:

Problem 1Difficulty: Mastery

Use the final process flowchart. Which sequence best summarizes normal meiosis and its outcome?

AHomolog separation, fertilization, DNA deletion, sister chromatid pairing, diploid gametes

BDNA replication, sister chromatid separation, homolog pairing, second DNA replication, four diploid cells

CFertilization, homolog pairing, mitosis, chromosome doubling, haploid zygotes

DDNA replication, homolog pairing and crossing over, homolog separation, sister chromatid separation, haploid gametes

Solution & Explanation:Normal meiosis begins after DNA replication, pairs homologs in prophase I, separates homologs in meiosis I, separates sister chromatids in meiosis II, and produces haploid gametes.

Problem 2Difficulty: Mastery

Use the chromosome-painting illustration. At the end of meiosis II, one gamete contains a chromosome with both maternal and paternal colored segments. What does this show?

AFertilization occurred before DNA replication, producing a diploid gamete.

BNo homologous chromosomes paired during meiosis I.

CCrossing over occurred before homologs separated, and meiosis II separated chromatids into gametes.

DThe gamete must contain both homologs of every chromosome pair.

Solution & Explanation:Mixed maternal and paternal segments on one chromosome indicate recombination from crossing over in prophase I. Meiosis II then separated chromatids so a recombinant chromosome entered a gamete.

Problem 3Difficulty: Mastery

Use the monosomy model. A gamete missing chromosome 5 fuses with a normal gamete. What is the resulting zygote condition for chromosome 5?

A2n + 1, trisomic for chromosome 5

B2n - 1, monosomic for chromosome 5

Cn + 1, haploid with an extra chromosome 5

D4n, tetraploid for all chromosomes

Solution & Explanation:A gamete missing one chromosome contributes n - 1. After fertilization with a normal n gamete, the zygote has 2n - 1 for that chromosome.

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QWhat grade level and standards does this worksheet align with?

This worksheet is designed specifically for Biology Science students. It aligns with educational standard BIO.10.62 (National: NGSS HS-LS3-1; HS-LS3-2; DCI LS3.A, LS3.B; CCSS RST.9-10.3; RST.9-10.7; AP Biology IST-3. State frameworks: TX TEKS BIO.8A; FL NGSSS SC.912.L.16.16, SC.912.L.16.17; VA SOL BIO.5d; CA NGSS/NYSSLS HS-LS3-1, HS-LS3-2.).