Free Printable WorksheetScienceGrade 10Science CurriculumBIO.10.67

10.67 Sex Linked Traits and Pedigrees Worksheet

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Worksheet Overview & Skills Covered

Core academic competencies and curriculum alignment

This Biology Science worksheet provides structured practice on 10.67 Sex Linked Traits and Pedigrees. Students are guided through targeted exercises that build foundational understanding, computational accuracy, and critical thinking skills.

Sex-Linked Traits and Pedigrees: Students interpret pedigrees and identify autosomal, sex-linked, dominant, recessive, carrier, and inheritance-risk patterns. Rigor range: standard concept checks through honors/Pre-AP/AP-ready sequence, probability, pedigree, population, and bioethics analysis. Aligned to FreeK12Practice High School Biology Curriculum Crosswalk (NGSS/NRC Framework; CCSS Literacy and Mathematics; AP Biology enrichment; Texas TEKS Biology; Florida NGSSS/CPALMS Biology; Virginia SOL Biology; California NGSS and New York State Science Learning Standards) BIO.10.67 - Sex-Linked Traits and Pedigrees: Corresponding standards copied from the curriculum for skill 10.67: National: NGSS HS-LS3-3; DCI LS3.B; CCSS HSS.CP.A.1-5; RST.9-10.7; AP Biology IST-3, SP5. State frameworks: TX TEKS BIO.8B; FL NGSSS SC.912.L.16.1, SC.912.L.16.2; VA SOL BIO.5c; CA NGSS/NYSSLS HS-LS3-3.

Whether you are an educator preparing classroom handouts, a tutor reinforcing weekly topics, or a parent supporting homeschool learning, this printable resource gives students the deliberate practice required to achieve subject fluency and master state standards.

Grade

Biology

Subject

Science

Domain

Science Curriculum

Formats

PDF & DOCX

Sample Practice Problems

Preview the types of problems and questions covered in this worksheet

Below are sample questions representative of the exercises included on this worksheet and related 10.67 Sex Linked Traits and Pedigrees skill assessments:

Problem 1Difficulty: Mastery

Use the family sequencing display shown. Affected males are hemizygous for the same X-linked variant, their mothers are heterozygous and unaffected, and no affected father-to-son transmission is observed. Which conclusion is best supported?

AThe evidence supports Y-linked inheritance through affected fathers.

BThe evidence supports an X-linked recessive inheritance pattern.

CThe evidence supports autosomal dominant inheritance with equal father-to-son transmission.

DThe evidence rules out sex-linked inheritance because mothers are unaffected.

Solution & Explanation:Hemizygous affected males, heterozygous unaffected mothers, and lack of father-to-son transmission are strong evidence for X-linked recessive inheritance.

Problem 2Difficulty: Mastery

Why can a new mutation complicate pedigree classification?

AA new allele can create an affected child even when neither parent shows the expected pattern.

BNew mutations always prove Y-linked inheritance.

CNew mutations prevent alleles from being passed to future generations.

DNew mutations make all pedigree symbols meaningless.

Solution & Explanation:Most pedigree rules describe inherited alleles, but a new mutation can produce an affected individual without the usual family history.

Problem 3Difficulty: Mastery

For an X-linked recessive trait, an affected father X^a Y and a carrier mother X^A X^a have a child whose sex is not specified. What is the probability that the child inherits the X^a allele and is either affected or a carrier?

A1/2

B3/4

C1/4

Solution & Explanation:All daughters inherit X^a from the father, which accounts for 1/2 of all children. Half of sons inherit X^a from the mother, adding 1/4. Total with X^a is 3/4.

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QWhat grade level and standards does this worksheet align with?

This worksheet is designed specifically for Biology Science students. It aligns with educational standard BIO.10.67 (Corresponding standards copied from the curriculum for skill 10.67: National: NGSS HS-LS3-3; DCI LS3.B; CCSS HSS.CP.A.1-5; RST.9-10.7; AP Biology IST-3, SP5. State frameworks: TX TEKS BIO.8B; FL NGSSS SC.912.L.16.1, SC.912.L.16.2; VA SOL BIO.5c; CA NGSS/NYSSLS HS-LS3-3.).