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8.97 Translate DNA Bases to Simple Codons (Conceptual) Worksheet

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Worksheet Overview & Skills Covered

Core academic competencies and curriculum alignment

This Grade 8 Science worksheet provides structured practice on 8.97 Translate DNA Bases to Simple Codons (Conceptual). Students are guided through targeted exercises that build foundational understanding, computational accuracy, and critical thinking skills.

Translate DNA Bases to Simple Codons (Conceptual) - Which use best a simplified codon table to connect DNA base sequences to amino acids (for concept only, not memorization)? (NGSS MS‑LS3‑1 (conceptual); TEKS §112.28 Grade 8; FL NGSSS; VA SOL; MA STE)

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Grade

Grade 8

Subject

Science

Domain

Science Curriculum

Formats

PDF & DOCX

Sample Practice Problems

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Below are sample questions representative of the exercises included on this worksheet and related 8.97 Translate DNA Bases to Simple Codons (Conceptual) skill assessments:

Problem 1Difficulty: Mastery
A research group shows students three sequences with a key: ATG = Methionine, GCT = Alanine, GCC = Alanine, TAA = Stop, and CAG = Glutamine. Sequence 1: ATG-GCT-CAG-TAA. Sequence 2: ATG-GCC-CAG-TAA. Sequence 3: ATG-TAA-CAG-TAA. Which conclusion is best?
AAll three sequences make the same amino acid chain
BSequences 1 and 2 make the same amino acid chain, but Sequence 3 is shorter
CSequence 2 is shorter than Sequence 3 because GCC is a stop codon
DSequence 1 and Sequence 3 make the same chain because both end with TAA
Solution & Explanation:GCT and GCC both code for Alanine, so Sequences 1 and 2 match. Sequence 3 has an earlier stop codon and therefore makes a shorter chain.
Problem 2Difficulty: Mastery
A teacher asks which statement best summarizes what a simplified DNA codon table helps students do. Which answer is best aligned to this practice skill?
AIdentify every organelle inside a cell from a microscope image
BMeasure the mass of atoms in a chemical equation
CConnect DNA base triplets to amino acids and predict simple effects of sequence changes
DExplain weather patterns using air pressure maps
Solution & Explanation:A simplified codon table is used to connect triplets of DNA bases to amino acids and reason about how sequence changes can affect a protein.
Problem 3Difficulty: Mastery
A student wants to change only the second amino acid in ATG-GTT-TAC-TAA. The key shows ATG = Methionine, GTT = Valine, GTC = Valine, GAT = Aspartic acid, TAC = Tyrosine, and TAA = Stop. Which edit best meets that goal?
AChange GTT to GAT
BChange GTT to GTC
CChange TAC to TAA
DDelete the first base of the sequence
Solution & Explanation:Changing GTT to GAT changes the second amino acid from Valine to Aspartic acid while leaving the rest of the reading frame intact.

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QWhat grade level and standards does this worksheet align with?

This worksheet is designed specifically for Grade 8 Science students. It aligns with educational standard 8.97 (Learners practice using a simplified DNA codon table to translate DNA triplets into amino acid chains, recognize stop signals, and compare how sequence changes can affect a protein.).

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