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Explain a Biological Mechanism
Grade Level
AP Biology
APB.002 Explain a Biological Mechanism
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A lysosomal enzyme is synthesized but secreted outside the cell instead of delivered to lysosomes. Analysis shows it lacks a mannose-6-phosphate tag. Which explanation best connects the missing tag to the sorting outcome?
A
The tag normally provides the enzyme's catalytic amino acids, so without it the enzyme becomes DNA.
B
Secreted enzymes are always transported to lysosomes by diffusion after leaving the cell.
C
Lysosomes make mannose-6-phosphate only after enzymes have already digested wastes.
D
The tag normally directs the enzyme to lysosomes; without it, the default secretory pathway carries the enzyme out of the cell.
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