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Receptor-Domain Mutations
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AP Biology
APB.221 Receptor-Domain Mutations
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A receptor is engineered with the extracellular and membrane domains of receptor A and the intracellular domain of receptor B. Ligand A is added, and pathway B becomes active. Which conclusion is best supported?
A
The extracellular domain of receptor A must contain all enzymes for pathway B.
B
The membrane domain prevents all domain-swap receptors from signaling.
C
Ligand A directly activates pathway B without a receptor.
D
The intracellular domain determines the downstream pathway once the extracellular domain receives the signal.
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