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Respiration Perturbation Analysis [Mini Skill]
Grade Level
AP Biology
APB.204 Respiration Perturbation Analysis [Mini Skill]
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A mitochondrial preparation receives NADH-linked substrates, oxygen, and ADP. An inhibitor of ATP synthase is added. Which prediction best describes oxygen consumption compared with a direct complex IV inhibitor?
A
ATP synthase inhibition would raise oxygen consumption more than control, while complex IV inhibition would make ATP synthase faster.
B
ATP synthase inhibition would lower oxygen consumption indirectly, while complex IV inhibition would block terminal electron transfer directly.
C
Both treatments would increase oxygen consumption because both strengthen proton flow through ATP synthase.
D
Only ATP synthase inhibition would prevent oxygen from accepting electrons at complex IV.
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