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RNA Primers and DNA Polymerase
Grade Level
AP Biology
APB.293 RNA Primers and DNA Polymerase
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A chromosome region has many replication origins, and DNA polymerase is recruited to each origin before primase acts. Why is recruitment alone insufficient for new strand synthesis?
A
Recruitment prevents DNA polymerase from recognizing complementary base pairs.
B
The polymerase still lacks a primer-template 3' end at each newly opened template.
C
Recruitment changes all dNTPs into ribonucleotides, blocking DNA synthesis.
D
Recruitment causes ligase to seal the origin before helicase arrives.
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